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Cyproheptadine Hydrochloride

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Description and usage

In the US, prescription cyproheptadine is indicated for the treatment of various allergic symptomatologies – including dermatographia, rhinitis, conjunctivitis, and urticaria – as well as adjunctive therapy in the management of anaphylaxis following treatment with epinephrine. In Canada, cyproheptadine is available over-the-counter and is indicated for the treatment of pruritus and for appetite stimulation. In Australia, cyproheptadine is additionally indicated for the treatment vascular headaches.

Cyproheptadine is also used off-label for the treatment of serotonin syndrome.



General Data

Chemical Name: Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride, sesquihydrate.
4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine hydrochloride sesquihydrate.


Cyproheptadine Hydrochloride

Cas no.: 41354-29-4
Molecular formula: C21H21N,HCl,1½H2O
Molecular weight: 350.88 g/mol


BP2020 & USP43